| Primary information |
|---|
| ID | 30303 |
| Uniprot ID | P28222 |
| Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B) (5-HT-1D-beta) (Serotonin 1D beta receptor) (S12). |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Post Translational Modification | Phosphorylated. Desensitization of the receptor may be mediated by its phosphorylation. Palmitoylated. |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin); a biogenic hormone that functions as a neurotransmitter; a hormone; and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
| Length | 390 |
| Molecular Weight | 43568 |
| Reference | NA |
| Hormone | NA |
| PDB ID | 2G1X;
|