Primary information |
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ID | 30178 |
Uniprot ID | Q26622 |
Description | Orphan steroid hormone receptor 2 (SpSHR2). |
Organism | Strongylocentrotus purpuratus |
Txonomy | Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa;Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae;Strongylocentrotus. |
Subcellular Location | Cytoplasm. Nucleus. Note=The subcellular location of isoform 1 alters throughout development. In the |
Developmental Stage | Expressed both maternally and zygotically. Present in the unfertilized egg and in all embryonic stages up to the pluteus stage; followed by depletion of expression in the late embryo. Expression starts again just prior to metamorphosis in larva at 35 days post fertilization. Also expressed in adults |
Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Post Translational Modification | NA |
Function | Orphan nuclear receptor. Binds to the hormone response element in the upstream promoter region of the CYIIIB gene in vitro. Both isoform 1 and isoform 2 bind DNA. |
Length | 583 |
Molecular Weight | 63853 |
Reference | NA |
Hormone | NA |
PDB ID | NA
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