Detailed description page of Hmrbase2

This page displays user query in tabular form.

30177 details
Primary information
ID30177
Uniprot IDP08689
DescriptionSex hormone-binding globulin precursor (SHBG) (Sex steroid-bindingprotein) (SBP) (Testis-specific androgen-binding protein) (ABP).
OrganismRattus norvegicus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular LocationSecreted. Note=In testis; it is synthesized by the Sertoli cells; secreted into the lumen of the sem
Developmental StageIn the fetal liver; expressed from day 14 to day 17 after conception.
SimilarityContains 2 laminin G-like domains.
Post Translational ModificationNA
FunctionFunctions as an androgen transport protein; but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone; testosterone; and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
Length403
Molecular Weight44533
ReferenceNA
HormoneNA
PDB IDNA