Primary information |
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ID | 30177 |
Uniprot ID | P08689 |
Description | Sex hormone-binding globulin precursor (SHBG) (Sex steroid-bindingprotein) (SBP) (Testis-specific androgen-binding protein) (ABP). |
Organism | Rattus norvegicus |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular Location | Secreted. Note=In testis; it is synthesized by the Sertoli cells; secreted into the lumen of the sem |
Developmental Stage | In the fetal liver; expressed from day 14 to day 17 after conception. |
Similarity | Contains 2 laminin G-like domains. |
Post Translational Modification | NA |
Function | Functions as an androgen transport protein; but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone; testosterone; and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. |
Length | 403 |
Molecular Weight | 44533 |
Reference | NA |
Hormone | NA |
PDB ID | NA
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