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30175 details
Primary information
ID30175
Uniprot IDQ62588
DescriptionSex hormone-binding globulin precursor (SHBG) (Sex steroid-bindingprotein) (SBP) (Testis-specific androgen-binding protein) (ABP).
OrganismPhodopus sungorus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Phodopus.
Subcellular LocationSecreted. Note=In testis; it is synthesized by the Sertoli cells; secreted into the lumen of the sem
Developmental StageNA
SimilarityContains 2 laminin G-like domains.
Post Translational ModificationDifferentially glycosylated in liver (SHBG) and testis (ABP).
FunctionFunctions as an androgen transport protein; but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone; testosterone; and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
Length399
Molecular Weight43842
ReferenceNA
HormoneNA
PDB IDNA