| Primary information |
|---|
| ID | 30173 |
| Uniprot ID | P04278 |
| Description | Sex hormone-binding globulin precursor (SHBG) (Sex steroid-bindingprotein) (SBP) (Testis-specific androgen-binding protein) (ABP)(Testosterone-estrogen-binding globulin) (Testosterone-estradiol-bindin |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Secreted. Note=In testis; it is synthesized by the Sertoli cells; secreted into the lumen of the sem |
| Developmental Stage | NA |
| Similarity | Contains 2 laminin G-like domains. |
| Post Translational Modification | NA |
| Function | Functions as an androgen transport protein; but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone; testosterone; and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. |
| Length | 402 |
| Molecular Weight | 43779 |
| Reference | NA |
| Hormone | NA |
| PDB ID | 1D2S; 1F5F; 1KDK; 1KDM; 1LHN; 1LHO; 1LHU; 1LHV; 1L |