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30171 details
Primary information
ID30171
Uniprot IDQ9GK30
DescriptionParathyroid hormone-related protein precursor (PTH-rP) (PTHrP)(Fragment).
OrganismOvis aries
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular LocationCytoplasm. Nucleus. Secreted
Developmental StageNA
SimilarityBelongs to the parathyroid hormone family.
Post Translational ModificationThere are several secretory forms; including osteostatin; arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine; autocrine and endocrine actions.
FunctionNeuroendocrine peptide which is a critical regulator of cellular and organ growth; development; migration; differenciation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth.
Length121
Molecular Weight13658
ReferenceNA
HormoneNA
PDB IDNA