| Primary information |
|---|
| ID | 30170 |
| Uniprot ID | Q9GLC7 |
| Description | Parathyroid hormone-related protein precursor (PTH-rP) (PTHrP)[Contains- Osteostatin]. |
| Organism | Oryctolagus cuniculus |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
| Subcellular Location | Cytoplasm. Nucleus. Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the parathyroid hormone family. |
| Post Translational Modification | There are several secretory forms; including osteostatin; arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine; autocrine and endocrine actions. |
| Function | Neuroendocrine peptide which is a critical regulator of cellular and organ growth; development; migration; differenciation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Osteostatin is a potent inhibitor of osteoclastic bone resorption. |
| Length | 177 |
| Molecular Weight | 20005 |
| Reference | NA |
| Hormone | NA |
| PDB ID | NA
|