| Primary information |
|---|
| ID | 30162 |
| Uniprot ID | P28069 |
| Description | Pituitary-specific positive transcription factor 1 (Pit-1) (Growthhormone factor 1) (GHF-1). |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Nucleus |
| Developmental Stage | NA |
| Similarity | Belongs to the POU transcription factor family. Class- 1 subfamily. Contains 1 homeobox DNA-binding domain. Contains 1 POU-specific domain. |
| Post Translational Modification | NA |
| Function | Transcription factor involved in the specification of the lactotrope; somatotrope; and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'- TAAAT-3'. |
| Length | 291 |
| Molecular Weight | 32912 |
| Reference | NA |
| Hormone | NA |
| PDB ID | NA
|