Primary information |
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ID | 30070 |
Uniprot ID | Q9Y618 |
Description | Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator ofretinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-;retinoic-acid-receptor-associated corepressor) (T3 receptor-associati |
Organism | Homo sapiens |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular Location | Nucleus |
Developmental Stage | NA |
Similarity | Belongs to the N-CoR nuclear receptor corepressors family. Contains 2 SANT domains. |
Post Translational Modification | NA |
Function | Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation; thus preventing access of the basal transcription. |
Length | 2517 |
Molecular Weight | 274034 |
Reference | NA |
Hormone | NA |
PDB ID | 1KKQ; 1R2B; 1XC5; 2ODD;
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