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30046 details
Primary information
ID30046
Uniprot IDP33244
DescriptionNuclear hormone receptor FTZ-F1 (FTZ-F1 alpha).
OrganismDrosophila melanogaster
TxonomyEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular LocationNucleus
Developmental StageFirst appears in blastoderm embryos. It is absent in subsequent embryo stages; and then reappears in late embryogenesis to be found in larvae; pupae and adults.
SimilarityBelongs to the nuclear hormone receptor family. NR5 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionActs as a cofactor to fushi tarazu (ftz). Facilitates the binding of ftz to DNA. Binds the sequence element 5'- YCYYGGYCR-3' in the zebra element of ftz. Probably also functions as a receptor for a yet unknown ligand.
Length1027
Molecular Weight108418
ReferenceNA
HormoneNA
PDB ID2IZ2;