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30042 details
Primary information
ID30042
Uniprot IDO08580
DescriptionSteroid hormone receptor ERR1 (Estrogen-related receptor; alpha) (ERR-alpha) (Estrogen receptor-like 1) (Fragment).
OrganismMus musculus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular LocationNucleus
Developmental StageExpressed in an organ specific manner through mid-to late embryonic development with persistent high-level expression in brown adipose tissue and intestinal mucosa.
SimilarityBelongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationPhosphorylated (Probable).
FunctionBinds to an ERR-alpha response element (ERRE) containing a single consensus half-site; 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus.
Length462
Molecular Weight49281
ReferenceNA
HormoneNA
PDB IDNA