Primary information |
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ID | 30042 |
Uniprot ID | O08580 |
Description | Steroid hormone receptor ERR1 (Estrogen-related receptor; alpha) (ERR-alpha) (Estrogen receptor-like 1) (Fragment). |
Organism | Mus musculus |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular Location | Nucleus |
Developmental Stage | Expressed in an organ specific manner through mid-to late embryonic development with persistent high-level expression in brown adipose tissue and intestinal mucosa. |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Post Translational Modification | Phosphorylated (Probable). |
Function | Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site; 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus. |
Length | 462 |
Molecular Weight | 49281 |
Reference | NA |
Hormone | NA |
PDB ID | NA
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