| Primary information |
|---|
| ID | 30041 |
| Uniprot ID | P11474 |
| Description | Steroid hormone receptor ERR1 (Estrogen-related receptor; alpha) (ERR-alpha) (Estrogen receptor-like 1). |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Nucleus |
| Developmental Stage | NA |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | NA |
| Function | Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site; 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. |
| Length | 519 |
| Molecular Weight | 55440 |
| Reference | NA |
| Hormone | NA |
| PDB ID | 1XB7; 2PJL; 3D24;
|