Detailed description page of Hmrbase2

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30038 details
Primary information
ID30038
Uniprot IDQ9BY15
DescriptionEGF-like module-containing mucin-like hormone receptor-like 3precursor (EGF-like module-containing mucin-like receptor EMR3).
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; multi-pass membrane protein. Subunit alpha- Secreted; extracellular space. Note=A sol
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 2 EGF-like domains. Contains 1 GPS domain.
Post Translational ModificationProteolytically cleaved into 2 subunits; an extracellular alpha subunit and a seven-transmembrane subunit.
FunctionReceptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils.
Length652
Molecular Weight72593
ReferenceNA
HormoneNA
PDB IDNA