| Primary information |
|---|
| ID | 17384 |
| Uniprot ID | P01374 |
| Description | Lymphotoxin-alpha (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1) |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted Membrane. Note=The homotrimer is secreted The heterotrimer is membrane-associated. |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1; TNFRSF1B/TNFBR and TNFRSF14/HVEM |
| Length | 205 |
| Molecular Weight | 22297 |
| Name | Lymphotoxin-alpha |
| Sequence | PGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL |
| Sequence map | 38-25 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | P36941; P19438 |
| Domain | NA |
| Pharmaceutical Use | NA
|