| Primary information |
|---|
| ID | 17380 |
| Uniprot ID | P10600 |
| Description | Transforming growth factor beta-3 proprotein [Cleaved into- Latency-associated peptide (LAP); Transforming growth factor beta-3 (TGF-beta-3)] |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | [Latency-associated peptide]- Secreted; extracellular space; extracellular matrix |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | NA |
| Post Translational Modification | Transforming growth factor beta-3 proprotein- The precursor proprotein is cleaved in the Golgi apparatus to form Transforming growth factor beta-3 (TGF-beta-3) and Latency-associated peptide (LAP) cha |
| Function | Transforming growth factor beta-3 proprotein- Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains; which constitute the regulatory and active subunit of TGF-beta-3; respectively. |
| Length | 412 |
| Molecular Weight | 47328 |
| Name | Latency-associated peptide |
| Sequence | STCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR |
| Sequence map | 29 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | P37173; Q6EMK4 |
| Domain | NA |
| Pharmaceutical Use | NA
|