Detailed description page of Hmrbase2

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17354 details
Primary information
ID17354
Uniprot IDP04090-1
DescriptionProrelaxin H2 [Cleaved into- Relaxin B chain; Relaxin A chain]
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityNA
Tissue SpecificityIsoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta; decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate glan
Post Translational ModificationNA
FunctionRelaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy; promoting growth of pubic ligaments and ripening of the cervix.
Length185
Molecular Weight21043
NameNA
SequenceNA
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorQ8WXD0
DomainNA
Pharmaceutical UseNA