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17333 details
Primary information
ID17333
Uniprot IDP02818
DescriptionOsteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityNA
Tissue SpecificityNA
Post Translational ModificationGamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
FunctionConstitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
Length100
Molecular Weight10963
NameOsteocalcin
SequenceLYQWLGAPVPYPDPLEPRREVCELNPDCDELADHIGFQEAYRRFYGPV
Sequence map53-40
PDB IDNA
DrugpediaNA
ReceptorQ5T6X5
DomainNA
Pharmaceutical UseNA