| Primary information |
|---|
| ID | 17330 |
| Uniprot ID | P12838 |
| Description | Defensin alpha 4 (Corticostatin HP-4) (HNP-4) (HP-4) (Neutrophil defensin 4) |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | Expressed in neutrophils |
| Post Translational Modification | The three-dimensional structure formed by the three intramolecular disulfide bridges is indispensable for effective bacterial killing. |
| Function | Host-defense peptide that has antimicrobial activity against Gram-negative bacteria; and to a lesser extent also against Gram-positive bacteria and fungi |
| Length | 97 |
| Molecular Weight | 10504 |
| Name | NA |
| Sequence | NA |
| Sequence map | NA |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | Q07954 |
| Domain | NA |
| Pharmaceutical Use | NA
|