| Primary information |
|---|
| ID | 17313 |
| Uniprot ID | P55773 |
| Description | C-C motif chemokine 23 (CK-beta-8) (CKB-8) (Macrophage inflammatory protein 3) (MIP-3) (Myeloid progenitor inhibitory factor 1) (MPIF-1) (Small-inducible cytokine A23) [Cleaved into- CCL23(19-99); CCL23(22-99); CCL23(27-99); CCL23(30-99)] |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | High levels in adult lung; liver; skeletal muscle and pancreas. Moderate levels in fetal liver; adult bone marrow and placenta. The short form is the major species and the longer form was detected onl |
| Post Translational Modification | NA |
| Function | Shows chemotactic activity for monocytes; resting T-lymphocytes; and neutrophils; but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99); CCL23(22-99); CCL23(27-99); CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. |
| Length | 120 |
| Molecular Weight | 13443 |
| Name | C-C motif chemokine 23 |
| Sequence | VTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN |
| Sequence map | 24 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | P32246 |
| Domain | NA |
| Pharmaceutical Use | NA
|