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17310 details
Primary information
ID17310
Uniprot IDP78556
DescriptionC-C motif chemokine 20 (Beta-chemokine exodus-1) (CC chemokine LARC) (Liver and activation-regulated chemokine) (Macrophage inflammatory protein 3 alpha) (MIP-3-alpha) (Small-inducible cytokine A20) [Cleaved into- CCL20(1-67); CCL20(1-64); CCL20(2-70)]
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityNA
Tissue SpecificityExpressed in the seminal plasma; endometrial fluid and follicular fluid
Post Translational ModificationC-terminal processed forms which lack 1; 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
FunctionActs as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions
Length96
Molecular Weight10762
NameC-C motif chemokine 20
SequenceSNFDCCLGYTDRILHPKFIVGFTRQLANEGCDINAIIFHTKKKLSVCANPKQTWVKYIVRLLSKKVKNM
Sequence map28-36
PDB IDNA
DrugpediaNA
ReceptorP51684
DomainNA
Pharmaceutical UseNA