| Primary information |
|---|
| ID | 17309 |
| Uniprot ID | Q16663 |
| Description | C-C motif chemokine 15 (Chemokine CC-2) (HCC-2) (Leukotactin-1) (LKN-1) (MIP-1 delta) (Macrophage inflammatory protein 5) (MIP-5) (Mrp-2b) (NCC-3) (Small-inducible cytokine A15) [Cleaved into- CCL15(22-92); CCL15(25-92); CCL15(29-92)] |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | Most abundant in heart; skeletal muscle and adrenal gland. Lower levels in placenta; liver; pancreas and bone marrow. CCL15 |
| Post Translational Modification | NA |
| Function | Chemotactic factor that attracts T-cells and monocytes; but not neutrophils; eosinophils; or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92); CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15. |
| Length | 113 |
| Molecular Weight | 12236 |
| Name | C-C motif chemokine 15 |
| Sequence | FTNDAETELMMSKLPLENPVVLNSFHFAADCCTSYISQSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI |
| Sequence map | 23-53 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | P32246; P51677 |
| Domain | NA |
| Pharmaceutical Use | NA
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