| Primary information |
|---|
| ID | 17301 |
| Uniprot ID | P80098 |
| Description | C-C motif chemokine 7 (Monocyte chemoattractant protein 3) (Monocyte chemotactic protein 3) (MCP-3) (NC28) (Small-inducible cytokine A7) |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | NA |
| Post Translational Modification | O-glycosylated. |
| Function | Chemotactic factor that attracts monocytes and eosinophils; but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1; CCR2 and CCR3. |
| Length | 99 |
| Molecular Weight | 11200 |
| Name | C-C motif chemokine 7 |
| Sequence | PVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL |
| Sequence map | 25-39 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | P32246; P41597; P51677; O00590 |
| Domain | NA |
| Pharmaceutical Use | NA
|