| Primary information |
|---|
| ID | 17295 |
| Uniprot ID | P10145 |
| Description | Interleukin-8 (IL-8) (C-X-C motif chemokine 8) (Chemokine (C-X-C motif) ligand 8) (Emoctakin) (Granulocyte chemotactic protein 1) (GCP-1) (Monocyte-derived neutrophil chemotactic factor) (MDNCF) (Monocyte-derived neutrophil-activating peptide) (MONAP) (Neutrophil-activating protein 1) (NAP-1) (Prote |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | NA |
| Post Translational Modification | Several N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes; leukcocytes and endothelial cells. In general; IL-8(1-77) is referred |
| Function | Chemotactic factor that mediates inflammatory response by attracting neutrophils; basophils; and T-cells to clear pathogens and protect the host from infection |
| Length | 99 |
| Molecular Weight | 11098 |
| Name | MDNCF-a |
| Sequence | GAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS |
| Sequence map | 22-39 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | P25024; P25025 |
| Domain | NA |
| Pharmaceutical Use | NA
|