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17282 details
Primary information
ID17282
Uniprot IDQ9NYY1
DescriptionInterleukin-20 (IL-20) (Cytokine Zcyto10)
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityNA
Tissue SpecificityExpressed in most tissues and five major cell types- epithelial cells
Post Translational ModificationNA
FunctionPro-inflammatory and angiogenic cytokine mainly secreted by monocytes and skin keratinocytes that plays crucial roles in immune responses; regulation of inflammatory responses; hemopoiesis; as well as epidermal cell and keratinocyte differentiation
Length176
Molecular Weight20072
NameInterleukin-20
SequenceKTLNLGSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGELDILLQWMEETE
Sequence map27-56
PDB IDNA
DrugpediaNA
ReceptorQ9UHF4; Q6UXL0; Q8N6P7
DomainNA
Pharmaceutical UseNA