| Primary information |
|---|
| ID | 17281 |
| Uniprot ID | P60568 |
| Description | Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin) |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance |
| Length | 153 |
| Molecular Weight | 17628 |
| Name | Interleukin-2 |
| Sequence | PTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT |
| Sequence map | 23-33 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | P01589; P14784 |
| Domain | NA |
| Pharmaceutical Use | Available under the name Proleukin (Chiron). Used in patients with renal cell carcinoma or metastatic melanoma.
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