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17272 details
Primary information
ID17272
Uniprot IDQ8TAD2
DescriptionInterleukin-17D (IL-17D) (Interleukin-27) (IL-27)
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityNA
Tissue SpecificityExpressed preferentially in adipose; skeletal muscle and CNS.
Post Translational ModificationNA
FunctionInduces expression of IL6; CXCL8/IL8; and CSF2/GM-CSF from endothelial cells.
Length202
Molecular Weight21893
NameInterleukin-17D
SequenceGAPRAGRRPARPRGCADRPEELLEQLYGRLAAGVLSAFHHTLQLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEPEKDADSINSSIDKQGAKLLLGPNDAPAGP
Sequence map19-22
PDB IDNA
DrugpediaNA
ReceptorQ6UWB1
DomainNA
Pharmaceutical UseNA