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17270 details
Primary information
ID17270
Uniprot IDQ16552
DescriptionInterleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8)
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityNA
Tissue SpecificityExpressed in memory Th17 cells
Post Translational ModificationN-glycosylated. Found both in glycosylated and nonglycosylated forms.
FunctionEffector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity
Length155
Molecular Weight17504
NameInterleukin-17A
SequenceITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA
Sequence map26-35
PDB IDNA
DrugpediaNA
ReceptorQ96F46
DomainNA
Pharmaceutical UseNA