| Primary information |
|---|
| ID | 17261 |
| Uniprot ID | P01574 |
| Description | Interferon beta (IFN-beta) (Fibroblast interferon) |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | Type I interferon cytokine that plays a key role in the innate immune response to infection; developing tumors and other inflammatory stimuli |
| Length | 187 |
| Molecular Weight | 22294 |
| Name | Interferon beta |
| Sequence | SYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN |
| Sequence map | 25-07 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | P48551 |
| Domain | NA |
| Pharmaceutical Use | Alleviates the exacerbations of multiple sclerosis (MS) (PubMed:8469318; PubMed:8469319). Available under the names Avonex (Biogen); Betaseron (Berlex) and Rebif (Serono) (PubMed:9345408). Betaseron i |