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17235 details
Primary information
ID17235
Uniprot IDO00182
DescriptionGalectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationCytoplasm
Developmental StageNA
SimilarityNA
Tissue SpecificityPeripheral blood leukocytes and lymphatic tissues. Expressed in lung; liver; breast and kidney with higher levels in tumor endothelial cells than normal endothelium
Post Translational ModificationNA
FunctionBinds galactosides
Length355
Molecular Weight39518
NameGalectin-9
SequenceAFSGSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQNPRTVPVQPAFSTVPFSQPVCFPPRPRGRRQKPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT
Sequence map6-55
PDB IDNA
DrugpediaNA
ReceptorQ8TDQ0
DomainContains two homologous but distinct carbohydrate-
Pharmaceutical UseNA