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17222 details
Primary information
ID17222
Uniprot IDQ9HCT0
DescriptionFibroblast growth factor 22 (FGF-22)
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityNA
Tissue SpecificityNA
Post Translational ModificationNA
FunctionPlays a role in the fasting response; glucose homeostasis; lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development.
Length170
Molecular Weight19663
NameFibroblast growth factor 22
SequencePSASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS
Sequence map25-50
PDB IDNA
DrugpediaNA
ReceptorP11362; P21802
DomainNA
Pharmaceutical UseNA