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17190 details
Primary information
ID17190
Uniprot IDQ9NRJ3
DescriptionC-C motif chemokine 28 (Mucosae-associated epithelial chemokine) (MEC) (Protein CCK1) (Small-inducible cytokine A28)
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityNA
Tissue SpecificityPreferentially expressed by epithelial cells of diverse tissues including normal and pathological colon; salivary gland; mammary gland; trachea and rectum. Also found in prostate; spleen; thyroid; pso
Post Translational ModificationNA
FunctionChemotactic activity for resting CD4; CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
Length127
Molecular Weight14280
NameC-C motif chemokine 28
SequenceEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLAAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHETYGHKTPY
Sequence map22-07
PDB IDNA
DrugpediaNA
ReceptorP46092; P51677
DomainNA
Pharmaceutical UseNA