Primary information |
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ID | 17190 |
Uniprot ID | Q9NRJ3 |
Description | C-C motif chemokine 28 (Mucosae-associated epithelial chemokine) (MEC) (Protein CCK1) (Small-inducible cytokine A28) |
Organism | Homo sapiens |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | NA |
Tissue Specificity | Preferentially expressed by epithelial cells of diverse tissues including normal and pathological colon; salivary gland; mammary gland; trachea and rectum. Also found in prostate; spleen; thyroid; pso |
Post Translational Modification | NA |
Function | Chemotactic activity for resting CD4; CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. |
Length | 127 |
Molecular Weight | 14280 |
Name | C-C motif chemokine 28 |
Sequence | EAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLAAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHETYGHKTPY |
Sequence map | 22-07 |
PDB ID | NA |
Drugpedia | NA |
Receptor | P46092; P51677 |
Domain | NA |
Pharmaceutical Use | NA
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