| Primary information |
|---|
| ID | 17186 |
| Uniprot ID | P13500 |
| Description | C-C motif chemokine 2 (HC11) (Monocyte chemoattractant protein 1) (Monocyte chemotactic and activating factor) (MCAF) (Monocyte chemotactic protein 1) (MCP-1) (Monocyte secretory protein JE) (Small-inducible cytokine A2) |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | Expressed in the seminal plasma; endometrial fluid and follicular fluid |
| Post Translational Modification | Processing at the N-terminus can regulate receptor and target cell selectivity (PubMed-8627182). Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattr |
| Function | Acts as a ligand for C-C chemokine receptor CCR2 |
| Length | 99 |
| Molecular Weight | 11025 |
| Name | C-C motif chemokine 2 |
| Sequence | PDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT |
| Sequence map | 25-39 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | Q9NPB9; P41597; P51679; O00590 |
| Domain | NA |
| Pharmaceutical Use | NA
|