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17184 details
Primary information
ID17184
Uniprot IDP0DP23
DescriptionCalmodulin-1
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationCytoplasm; cytoskeleton; spindle
Developmental StageNA
SimilarityNA
Tissue SpecificityNA
Post Translational ModificationUbiquitination results in a strongly decreased activity.
FunctionCalmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes; ion channels; aquaporins and other proteins through calcium-binding
Length149
Molecular Weight16838
NameCalmodulin-1
SequenceDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
Sequence map4-29
PDB IDNA
DrugpediaNA
ReceptorQ8NER1
DomainThe N-terminal and C-terminal lobes of CALM bind t
Pharmaceutical UseNA