Detailed description page of Hmrbase2

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17006 details
Primary information
ID17006
Uniprot IDE1ZZF9
DescriptionKininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into- Kininogen-1 heavy chain; T-kinin (Ile-Ser-Bradykinin); Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain;
OrganismCamponotus floridanus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular Locationsecreted
Developmental StageNA
SimilarityFMRFamide related peptide family
Tissue SpecificitySecreted in plasma. T-kinin is detected in malignant ovarian; colon and breast carcinomas; but not in benign tumors.
Post Translational ModificationT10 Phenylalanine amide
FunctionHave modulatory actions at skeletal neuromuscular junctions
Length644
Molecular Weight71
NameFMRFamide 3
SequenceGKNDLNFIRF
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA