Detailed description page of Hmrbase2

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16691 details
Primary information
ID16691
Uniprot IDP85863
DescriptionProSAAS (Proprotein convertase subtilisin/kexin type 1 inhibitor) (Proprotein convertase 1 inhibitor) (pro-SAAS) [Cleaved into- KEP; Big SAAS (b-SAAS); Little SAAS (l-SAAS); Big PEN-LEN (b-PEN-LEN) (SAAS CT(1-49)); PEN; PEN-20; Little LEN (l-LEN); Big LEN (b-LEN) (SAAS CT(25-40))]
OrganismSchistocerca gregaria
TxonomyRattus ; Murinae ; Muridae ; Muroidea ; Myomorpha ; Rodentia ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular Locationsecreted
Developmental StageExpressed by 12.5 dpc in essentially all differentiating neurons in the mantle layer of the myelencephalon; metencephalon; diencephalon; spinal cord and several sympathetic ganglia. During later stage
SimilarityPyrokinin family
Tissue SpecificityExpressed in adult brain (all major structural regions); adrenal gland (medulla) and spinal cord (dorsal and ventral horn). Expressed in pancreatic islands.
Post Translational ModificationT10 Leucine amide
FunctionHindgut‐stimulating activity
Length260
Molecular Weight27
NameSchistomyotropin-2
SequenceTSSLFPHPRL
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA