Detailed description page of Hmrbase2

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16683 details
Primary information
ID16683
Uniprot IDP85864
DescriptionCerebellin-1 (Brain protein D3) (Precerebellin) [Cleaved into- Cerebellin (CER); [des-Ser1]-cerebellin (des-Ser1-cerebellin)]
OrganismSchistocerca gregaria
TxonomyMus (subgenus); Mus ; Murinae ; Muridae ; Muroidea ; Myomorpha ; Rodentia ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular Locationsecreted
Developmental StageIn the developing brain; expressed as early as embryonic day 10-13; and transiently up-regulated during the late embryonic and neonatal periods. Cerebellin and [des-Ser1]-cerebellin are expressed as e
SimilarityPyrokinin family
Tissue SpecificityExpressed and secreted by presynaptic neurons; such as cerebellar granule cells. Following secretion; the protein binds to GRID2 on the postsynaptic Purkinje cell membranes. Expressed at the highest l
Post Translational ModificationT18 Valine amide
FunctionMyoactive
Length193
Molecular Weight21
NamePyrokinin
SequenceDGAETPGAAASLWFGPRV
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA