| Primary information |
|---|
| ID | 16089 |
| Uniprot ID | P55791 |
| Description | FMRFamide-18 (LucFMRFamide-18) |
| Organism | Sus scrofa |
| Txonomy | Lucilia ; Luciliinae ; Calliphoridae ; Oestroidea ; Calyptratae ; Schizophora ; Cyclorrhapha ; Eremoneura ; Muscomorpha ; Brachycera ; Diptera ; Endopterygota (cohort); Neoptera (infraclass); Pterygota (subclass); Dicondylia ; Insecta ; Hexapoda ; Pancrustacea ; Mandibulata ; Arthropoda ; Panarthropoda ; Ecdysozoa ; Protostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | secreted |
| Developmental Stage | NA |
| Similarity | Opioid neuropeptide precursor family |
| Tissue Specificity | Detected in the thoracic perisympathetic organs in larvae; and the dorsal ganglionic sheath in adults (at protein level). |
| Post Translational Modification | NA |
| Function | It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. When administered intracerebroventricularly into mice; this peptide induces hyperalgesia and decreases locomotor activity. |
| Length | 12 |
| Molecular Weight | 1 |
| Name | Nociceptin |
| Sequence | FGGFTGARKSARKLANQ |
| Sequence map | NA |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|