Detailed description page of Hmrbase2

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15857 details
Primary information
ID15857
Uniprot IDP0C0P5
DescriptionProtachykinin-1 (PPT) [Cleaved into- Substance P; Neurokinin A (NKA) (Neuromedin L) (Substance K); Neuropeptide gamma; C-terminal-flanking peptide]
OrganismBos taurus
TxonomyOryctolagus ; Leporidae ; Lagomorpha ; Glires ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular Locationsecreted
Developmental StageNA
SimilarityNeuropeptide S family
Tissue SpecificityNA
Post Translational ModificationNA
FunctionModulates arousal and anxiety. May play an important anorexigenic role. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations
Length115
Molecular Weight13
NameNeuropeptide S
SequenceSFRNGVGTGMKKTSFRRAKS
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA