| Primary information |
|---|
| ID | 15842 |
| Uniprot ID | P48645 |
| Description | FMRFamide-8 (LucFMRFamide-8) |
| Organism | Homo sapiens |
| Txonomy | Lucilia ; Luciliinae ; Calliphoridae ; Oestroidea ; Calyptratae ; Schizophora ; Cyclorrhapha ; Eremoneura ; Muscomorpha ; Brachycera ; Diptera ; Endopterygota (cohort); Neoptera (infraclass); Pterygota (subclass); Dicondylia ; Insecta ; Hexapoda ; Pancrustacea ; Mandibulata ; Arthropoda ; Panarthropoda ; Ecdysozoa ; Protostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | secreted |
| Developmental Stage | NA |
| Similarity | NmU family |
| Tissue Specificity | Detected in the thoracic perisympathetic organs in larvae; and the dorsal ganglionic sheath in adults (at protein level). |
| Post Translational Modification | T25 Asparagine amide |
| Function | Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans; NmU stimulates contractions of the ileum and urinary bladder. |
| Length | 9 |
| Molecular Weight | 1 |
| Name | Neuromedin-U-25 |
| Sequence | FRVDEEFQSPFASQSRGYFLFRPRN |
| Sequence map | NA |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | Q9HB89; Q9GZQ4 |
| Domain | NA |
| Pharmaceutical Use | NA
|