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13916 details
Primary information
ID13916
Uniprot IDP01042
DescriptionSecretogranin-2 (Chromogranin-C) (Secretogranin II) (SgII) [Cleaved into- Secretoneurin (SN); Manserin]
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular Locationsecreted
Developmental StageNA
SimilarityBradykinin family
Tissue SpecificityNA
Post Translational ModificationNA
FunctionInfluence in smooth muscle contraction;induction of hypotension;natriuresis and diuresis;decrease in blood glucose level;it is a mediator of inflammation and causes ; increase in vascular permeability;stimulation of nociceptors ; release of other mediators of inflammation ; it has a cardioprotective effect
Length617
Molecular Weight70
NameBradykinin
SequenceRPPGFSPFR
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorP46663; P30411; P46663; P30411
DomainNA
Pharmaceutical UseNA