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13670 details
Primary information
ID13670
Uniprot IDP40765
DescriptionCoatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into- Xenin (Xenopsin-related peptide); Proxenin] (Fragment)
OrganismCanis lupus familiaris
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Caniformia; Canidae (dog; coyote; wolf; fox); Canis; Canis lupus (Gray wolf); Canis lupus familiaris (Dog) (Canis familiaris)
Subcellular LocationNA
Developmental StageReleased into the circulation after a meal.
SimilarityNA
Tissue SpecificityGastric; duodenal and jejunal mucosa. Circulates in the blood. Seems to be confined to specific endocrine cells.
Post Translational ModificationNA
FunctionXenin stimulates exocrine pancreatic secretion. It inhibits pentagastrin-stimulated secretion of acid; to induce exocrine pancreatic secretion and to affect small and large intestinal motility. In the gut; xenin interacts with the neurotensin receptor.
Length35
Molecular Weight4
NameCoatomer subunit alpha
SequenceMLTKFETKSARVKGLSFHPKRPWIL
Sequence map600
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA