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13655 details
Primary information
ID13655
Uniprot IDP17251
DescriptionParathyroid hormone-related protein (PTH-rP) (PTHrP) [Cleaved into- Osteostatin (PTHrP[107-139])]
OrganismGallus gallus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae (turkeys); Phasianinae; Gallus; Gallus gallus (Chicken)
Subcellular LocationCytoplasm
Developmental StageNA
SimilarityBelongs to the parathyroid hormone family.
Tissue SpecificityNA
Post Translational ModificationThere are several secretory forms; including osteostatin; arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its
FunctionNeuroendocrine peptide which is a critical regulator of cellular and organ growth; development; migration; differentiation and survival and of epithelial calcium ion transport.
Length176
Molecular Weight20
NameParathyroid hormone-related protein
SequenceVSEHQLLHDKGKSIQDLRRRIFLQNLIEGVNTAEIRATSEVSPNPKPATNTKNYPVRFGSEDEGRYLTQETNKSQTYKEQPLKVSGKKKKAKPGKRKEQEKKKRRARSAWLNSGMYGSNVTESPVLDNSVTTHNHILR
Sequence map40-56
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA