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13646 details
Primary information
ID13646
Uniprot IDI7C2V3
DescriptionSpexin prohormone 1 (Spexin hormone) [Cleaved into- Spexin-1]
OrganismCarassius auratus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Otomorpha; Ostariophysi; Otophysi; Cypriniphysae; Cypriniformes (carps and others); Cyprinoidei; Cyprinidae; Cyprininae; Carassius; Carassius auratus (Goldfish)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the spexin family.
Tissue SpecificityExpressed in the anterior hypothalamus; ventromedial thalamic nucleus and medial longitudinal fasciculus of the brain (at protein level). Widely expressed. Expressed predominantly in the spleen; kidne
Post Translational ModificationNA
FunctionPlays a role in the regulation of food intake and body weight and in reproduction. May also play a role as a central modulator of cardiovascular and renal function and nociception.
Length102
Molecular Weight11
NameSpexin prohormone 1
SequencePMGSFQRRNWTPQAMLYLKGTQGRRFVSEDRNEGDLYDTIRLESQSQNTENLSISKAAAFLLNVLQQARDEGEPY
Sequence map28-42
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA