Primary information |
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ID | 13629 |
Uniprot ID | P30371 |
Description | Transforming growth factor beta-2 proprotein [Cleaved into- Latency-associated peptide (LAP); Transforming growth factor beta-2 (TGF-beta-2)] |
Organism | Gallus gallus |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae (turkeys); Phasianinae; Gallus; Gallus gallus (Chicken) |
Subcellular Location | [Latency-associated peptide]- Secreted; extracellular space; extracellular matrix |
Developmental Stage | NA |
Similarity | Belongs to the TGF-beta family. |
Tissue Specificity | NA |
Post Translational Modification | Transforming growth factor beta-2 proprotein- The precursor proprotein is cleaved in the Golgi apparatus to form Transforming growth factor beta-2 (TGF-beta-2) and Latency-associated peptide (LAP) cha |
Function | Transforming growth factor beta-2 proprotein- Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains; which constitute the regulatory and active subunit of TGF-beta-2; respectively. |
Length | 412 |
Molecular Weight | 47 |
Name | Transforming growth factor beta-2 proprotein |
Sequence | STCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPDEYPEPEEVPPEVISIYNSTRDLLQEKANHRAATCERERSDEEYYAKEVYKIDMQPFYPENAIPPSYYSLYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNSKARVSEQRIELYQVLKSKELSSPGQRYIDSKVVKTRAEGEWLSFDVTEAVHEWLHHRDRNLGFKISLHCPCCTFVPSNNYIIPNKSEEPEARFAGIDDYTYSSGDVKALKSNRKKYSGKTPHLLLMLLPSYRLESQQPSRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYHANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS |
Sequence map | 27-52 |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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