Primary information |
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ID | 13628 |
Uniprot ID | C6EVG7 |
Description | Natriuretic and helokinestatin peptides [Cleaved into- Helokinestatin-1 (HKS-1); Helokinestatin-2 (HKS-2); Helokinestatin-3 (HKS-3); Helokinestatin-4 (HKS-4); Natriuretic peptide] |
Organism | Heloderma suspectum cinctum |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Lepidosauria (lepidosaurs); Squamata (squamates); Bifurcata (split-tongued squamates); Unidentata; Episquamata; Toxicofera; Anguimorpha (anguimorph lizards); Neoanguimorpha (New World anguimorph lizards); Helodermatidae (beaded lizards); Heloderma; |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | In the C-terminal section; belongs to the natriuretic peptide family. |
Tissue Specificity | Expressed by the venom gland. |
Post Translational Modification | NA |
Function | Helokinestatin antagonizes the vasodilatory actions of bradykinin at the B2 bradykinin receptor (BDKRB2); with helokinestatin-1 being the most potent antagonist. |
Length | 178 |
Molecular Weight | 19 |
Name | NA |
Sequence | NA |
Sequence map | NA |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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