| Primary information |
|---|
| ID | 13627 |
| Uniprot ID | P0C7W2 |
| Description | Prosalusin (Torsin family 2 member A) (Torsin-2A) [Cleaved into- Salusin-beta] |
| Organism | Rattus norvegicus |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the ClpA/ClpB family. Torsin subfamily. |
| Tissue Specificity | Isoform 2 is ubiquitously expressed. |
| Post Translational Modification | NA |
| Function | Salusin may be a endocrine and/or paracrine factor able to increase intracellular calcium concentrations and induce cell mitogenesis. Salusin may also be a potent hypotensive peptide. |
| Length | 231 |
| Molecular Weight | 25 |
| Name | Prosalusin |
| Sequence | DVSFLRCSLGSFCECDFWPDLPGLECDLARHLAGQHLAKALVVKSLKAFVQDPAPSKPLVLSLHGWTGTGKSYVSSLLAQYLFRGGLRSPHVHHFSPIIHFPHPSHTEQYKNELKSWVQGNLTACGRSLFLFDEMDKLPPGLMEVLKPFLGPSWVVYGTNYRKAIFIFIRWLLAVWHHGGAAAGCCGPLPPPPAASCAPLCAQ |
| Sequence map | 31-51 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|