Detailed description page of Hmrbase2

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13620 details
Primary information
ID13620
Uniprot IDQ9TS44
DescriptionCholecystokinins (CCK) [Cleaved into- Cholecystokinin-58 (CCK58); Cholecystokinin-58 desnonopeptide ((1-49)-CCK58); Cholecystokinin-39 (CCK39); Cholecystokinin-33 (CCK33); Cholecystokinin-25 (CCK25); Cholecystokinin-18 (CCK18); Cholecystokinin-12 (CCK12); Cholecystokinin-8 (CCK8); Cholecystokinin-7
OrganismCanis lupus familiaris
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Caniformia; Canidae (dog; coyote; wolf; fox); Canis; Canis lupus (Gray wolf); Canis lupus familiaris (Dog) (Canis familiaris)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the gastrin/cholecystokinin family.
Tissue SpecificityNA
Post Translational ModificationThe precursor is cleaved by proteases to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas; binding to CCK-B receptors stimulates gastric acid secretion. cholecystokinin 58 and cholecystokinin 8; but not cholecystokinin 58 desnonopeptide; stimulate amylase release from the pancreas. cholecystokinin 58; but not cholecystokinin 8; increases bile-pancreatic volume.
Length58
Molecular Weight6
NameNA
SequenceNA
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA