Detailed description page of Hmrbase2

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13605 details
Primary information
ID13605
Uniprot IDA0A0B5A7N1
DescriptionCon-Ins F2b (Insulin 2b) [Cleaved into- Con-Ins F2b B chain; Con-Ins F2b A chain]
OrganismConus floridulus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Caenogastropoda; Neogastropoda; Conoidea; Conidae (cone shells); Conus; Lividoconus; Conus floridulus (Cone snail) (Lividoconus floridulus)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the insulin family.
Tissue SpecificityExpressed by the venom gland.
Post Translational ModificationNA
FunctionThis venom insulin facilitates prey capture by rapidly inducing hypoglycemic shock. Intraperitoneal injection of this peptide into zebrafish lowers blood glucose with the same potency than human insulin. In vivo; when applied to water; this peptide reduces overall locomotor activity of zebrafish larvae; observed as a significant decrease in the percentage of time spent swimming and movement frequency.
Length128
Molecular Weight13
NameNA
SequenceNA
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA