Detailed description page of Hmrbase2

This page displays user query in tabular form.

13604 details
Primary information
ID13604
Uniprot IDA0A0B5ABE4
DescriptionCon-Ins Q1b (Insulin 1b) [Cleaved into- Con-Ins Q1b B chain; Con-Ins Q1b A chain]
OrganismConus quercinus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Caenogastropoda; Neogastropoda; Conoidea; Conidae (cone shells); Conus; Lividoconus; Conus quercinus (Oak cone)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the insulin family.
Tissue SpecificityExpressed by the venom gland.
Post Translational ModificationNA
FunctionThis venom insulin facilitates prey capture by rapidly inducing hypoglycemic shock. Intraperitoneal injection of this peptide into zebrafish lowers blood glucose with the same potency than human insulin. In vivo; when applied to water; this peptide reduces overall locomotor activity of zebrafish larvae; observed as a significant decrease in the percentage of time spent swimming and movement frequency.
Length131
Molecular Weight14
NameNA
SequenceNA
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA