Detailed description page of Hmrbase2

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13602 details
Primary information
ID13602
Uniprot IDA0A0F7YYV0
DescriptionInsulin-like peptide-1 (ILP-1) [Cleaved into- ILP-1 B chain; ILP-1 A chain]
OrganismConus victoriae
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Caenogastropoda; Neogastropoda; Conoidea; Conidae (cone shells); Conus; Cylinder; Conus victoriae (Queen Victoria cone)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the insulin family.
Tissue SpecificityExpressed by the venom duct.
Post Translational ModificationNA
FunctionThis venom insulin facilitates prey capture by rapidly inducing hypoglycemic shock. Intraperitoneal injection of this peptide into zebrafish lowers blood glucose with the same potency than human insulin. In vivo; when applied to water; this peptide reduces overall locomotor activity of zebrafish larvae; observed as a significant decrease in the percentage of time spent swimming and movement frequency.
Length123
Molecular Weight13
NameNA
SequenceNA
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA