Primary information |
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ID | 13602 |
Uniprot ID | A0A0F7YYV0 |
Description | Insulin-like peptide-1 (ILP-1) [Cleaved into- ILP-1 B chain; ILP-1 A chain] |
Organism | Conus victoriae |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Caenogastropoda; Neogastropoda; Conoidea; Conidae (cone shells); Conus; Cylinder; Conus victoriae (Queen Victoria cone) |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the insulin family. |
Tissue Specificity | Expressed by the venom duct. |
Post Translational Modification | NA |
Function | This venom insulin facilitates prey capture by rapidly inducing hypoglycemic shock. Intraperitoneal injection of this peptide into zebrafish lowers blood glucose with the same potency than human insulin. In vivo; when applied to water; this peptide reduces overall locomotor activity of zebrafish larvae; observed as a significant decrease in the percentage of time spent swimming and movement frequency. |
Length | 123 |
Molecular Weight | 13 |
Name | NA |
Sequence | NA |
Sequence map | NA |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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